Monday, 8:15 p.m. ET | ESPN
Matchup rating: 37.4 | Spread: ARI -1.5 (55)
What to watch for: Cardinals quarterback Kyler Murray is 6-0 all time at AT&T Stadium. He went 5-0 while at Allen High School, including three state championships, and 1-0 with Oklahoma, winning the Big 12 championship. The Cowboys are well aware of what he means to Arizona's offense. "He has a unique skill set. He's so quick and explosive, and he can get the ball out of his hand very quickly," Dallas coach Mike McCarthy said. "Obviously he can make any throw, he can hit all the quadrants of the field, and he's leading the league in rushing as quarterbacks. So I think that in itself tells you the stress that he puts on your defense. ... He's a dynamic player and he's definitely the centerpiece of that offense." -- Todd Archer
Bold prediction: Murray will throw for 350 yards and run for another 100 in a reminder to everyone in the Dallas-Fort Worth metroplex that he's a legend there for a reason. -- Josh Weinfuss
Stat to know: The Cowboys have 11 turnovers this season, tied for most in the NFL. But the Cardinals have three takeaways, tied for the third fewest.
Betting nugget: Arizona is the only team in the NFL to see all five of its games go under the total. Read more.
Weinfuss' pick: Cardinals 34, Cowboys 24
Archer's pick: Cardinals 33, Cowboys 31
FPI prediction: ARI, 54.3% (by an average of 1.5 points)
Matchup must-reads: Cardinals LB Jones to have season-ending surgery ... Even without Prescott, Cowboys say plan stays the same on offense ... Hopkins credits Murray, Cardinals' playcalling for hot start ... Could Dak still get $100 million? NFL execs, coaches weigh in on QB's future